vial
Reference: CAN-P-400
Kit Type: Competitive ELISA
Kit Size: 96-well break-apart microplate
Sensitivity: 0.051 ng/mL
Sample Type: Human serum / 25 μL
Calibrator Range: 0.15–20 ng/mL
Total Assay Time: 80 minutes
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Note: When using the kit, the IFU version that is provided with the kit must be followed.

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Medical applications:

17α-Hydroxyprogesterone (17α-OHP)

The steroid 17α-hydroxyprogesterone is produced by the adrenal cortex and gonads. 17α-OHP has little progestational activity, but it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Cpd-S is produced by the 21-hydroxylation of 17α-OHP. Measurement of 17α-OHP is a useful indirect indicator of 21-hydroxlase activity. In congenital 21-hydroxylase defi ciency, the most common variety of congenital adrenal hyperplasia (CAH), 17α-OHP is secreted in abundant excess. Measurement of 17α-OHP is therefore valuable in the initial diagnosis of CAH.