Ref
CAN-P-400
Kit Type:
Competitive ELISA
Kit Size:
96-well break-apart microplate
Sensitivity:
0.051 ng/mL
Sample Type:
Human serum / 25 μL
Calibrator Range:
0.15–20 ng/mL
Total Assay Time:
80 minutes
Note: When using the kit, the IFU version that is provided with the kit must be followed.
- CAN:
- EU:
- USA:
The steroid 17α-hydroxyprogesterone is produced by the adrenal cortex and gonads. 17α-OHP has little progestational activity, but it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Cpd-S is produced by the 21-hydroxylation of 17α-OHP. Measurement of 17α-OHP is a useful indirect indicator of 21-hydroxlase activity. In congenital 21-hydroxylase defi ciency, the most common variety of congenital adrenal hyperplasia (CAH), 17α-OHP is secreted in abundant excess. Measurement of 17α-OHP is therefore valuable in the initial diagnosis of CAH.